The COVID-19 pandemic has revealed a need for communities across the United States to improve their ability to address large-scale public health crises that require robust and targeted efforts from many disparate entities. Healthy Davis Together is unique in that public and private partnerships were built into its core structure from the outset. These partnerships have led to significant improvements in health outcomes and strengthened community relationships. This paper provides an overview of the key partnerships that helped HDT put into practice a robust COVID-19 response strategy and offers learnings that other communities can apply to future public health and community resilience efforts.